The MutationTaster (MT) score is the probability that the prediction is true:
"Scores below 0.5 hence indicate, MT classifier comes to a different conclusion. A few SNPs listed in HapMap introduce premature stop codons and will cause NMD; these are likely to be mistaken for disease mutations." (MT documentation)
MutationTaster predicts an alteration as one of four possible types:
- D: disease causing - i.e. probably deleterious
- A: disease causing automatic - i.e. known to be deleterious, see section dbSNP / TGP / ClinVar / HGMD for details
- N: polymorphism - i.e. probably harmless
- P: polymorphism automatic - i.e. known to be harmless, see section dbSNP / TGP / ClinVar / HGMD for details.
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