---
title: Representation of zygosity for large cohort analyses
description: The zygosity representation shown below applies for multi-sample analyses larger than 10 samples and brings together information about both the zygosity and the status (affected - unaffected) of the s
---
[Skip to content](https://docs.varsome.com/en/representation-of-zygosity-for-large-cohort-analyses#main-content)
English
Show submenu for translations
[Submit a Support Request](https://docs.varsome.com/en/kb-tickets/new?hsLang=en) [Customer portal](https://docs.varsome.com/support-requests?hsLang=en)
[![varsome-new.png\]](https://docs.varsome.com/hs-fs/hubfs/varsome-new.png?height=40&name=varsome-new.png)](https://docs.varsome.com/en?hsLang=en)
- Editions
Show submenu for Editions
- [VarSome.com](https://landing.varsome.com/varsome)
- [VarSome Clinical](https://landing.varsome.com/varsome-clinical)
- [VarSome Premium](https://landing.varsome.com/varsome-premium)
- [VarSome API](https://landing.varsome.com/varsome-api)
- [VarSome Insights](https://landing.varsome.com/varsome-insights)
- About
Show submenu for About
- [The Company](https://saphetor.com/)
- [Contact Us](https://landing.varsome.com/contact)
- [Distributors](https://landing.varsome.com/distributors)
- [Become a Partner](https://landing.varsome.com/become-varsome-partner)
- [Community](https://varsome.com/community-contributions/)
- [Cite VarSome!](https://varsome.com/about/general/varsome-citations/)
- Resources
Show submenu for Resources
- [Datasources](https://varsome.com/datasources/)
- [Germline Classification](https://varsome.com/about/resources/germline-implementation/)
- [Somatic Classification](https://varsome.com/about/resources/somatic-implementation/)
- [CNV Classification](https://varsome.com/about/resources/sv-implementation/)
- [Help Center](https://docs.varsome.com/)
- [Library](https://landing.varsome.com/whitepapers)
- [IVDR](https://landing.varsome.com/ivdr-whitepaper)
- [Legal & Compliance](https://docs.varsome.com/en/legal-compliance)
- Blog
Show submenu for Blog
- [Platform Updates](https://updates.varsome.com/en)
- [Company News](https://news.varsome.com/en)
- [VarSome Annotated](https://blog.varsome.com/annotated)
Open main navigation
Close main navigation
- Editions
Show submenu for Editions
- [VarSome.com](https://landing.varsome.com/varsome)
- [VarSome Clinical](https://landing.varsome.com/varsome-clinical)
- [VarSome Premium](https://landing.varsome.com/varsome-premium)
- [VarSome API](https://landing.varsome.com/varsome-api)
- [VarSome Insights](https://landing.varsome.com/varsome-insights)
- About
Show submenu for About
- [The Company](https://saphetor.com/)
- [Contact Us](https://landing.varsome.com/contact)
- [Distributors](https://landing.varsome.com/distributors)
- [Become a Partner](https://landing.varsome.com/become-varsome-partner)
- [Community](https://varsome.com/community-contributions/)
- [Cite VarSome!](https://varsome.com/about/general/varsome-citations/)
- Resources
Show submenu for Resources
- [Datasources](https://varsome.com/datasources/)
- [Germline Classification](https://varsome.com/about/resources/germline-implementation/)
- [Somatic Classification](https://varsome.com/about/resources/somatic-implementation/)
- [CNV Classification](https://varsome.com/about/resources/sv-implementation/)
- [Help Center](https://docs.varsome.com/)
- [Library](https://landing.varsome.com/whitepapers)
- [IVDR](https://landing.varsome.com/ivdr-whitepaper)
- [Legal & Compliance](https://docs.varsome.com/en/legal-compliance)
- Blog
Show submenu for Blog
- [Platform Updates](https://updates.varsome.com/en)
- [Company News](https://news.varsome.com/en)
- [VarSome Annotated](https://blog.varsome.com/annotated)
- English
Show submenu for translations
- [Submit a Support Request](https://docs.varsome.com/en/kb-tickets/new)
- [Customer portal](https://docs.varsome.com/support-requests)
- [Contact us](https://docs.varsome.com/en/kb-tickets/new)
[Contact us](https://docs.varsome.com/en/kb-tickets/new?hsLang=en)
How can we help you?
- There are no suggestions because the search field is empty.
1. [VarSome Help Center](https://docs.varsome.com/en?hsLang=en)
2. [Analysis of the results](https://docs.varsome.com/en/analysis-of-the-results?hsLang=en)
3. [Results](https://docs.varsome.com/en/analysis-of-the-results?hsLang=en#results)
# Representation of zygosity for large cohort analyses
The zygosity representation shown below applies for multi-sample analyses larger than 10 samples and brings together information about both the zygosity and the status (affected - unaffected) of the samples at first glance.
In this layout, each type of zygosity found for a variant is shown only once with the respective box. Next to each box reside two numbers: the number in green font corresponds to the unaffected samples having this specific type of zygosity for this variant. The number in red font corresponds to the affected samples having this type of zygosity in the dataset.
Each box is associated with this pair of color-coded numbers which provides information about both the number of occurrences in the dataset and the status of these samples in a compact manner.
The "**Nearby variants in this sample**" tab is modified, as well to fit more efficiently large cohort analyses of more than 10 samples using the layout described for the "**Zygosity**" column.
[](https://lh7-rt.googleusercontent.com/docsz/AD_4nXcDBHoTB4-3Bhc3MfGU8YAMFHZjPdbny9GjOBtz0b6o2DVuA1V860b7BcEZQ0j10ValN0Jmf7iyxeJCfFNshkNSkRAQnVlbtOoueIZQcmHxmU9EapLzdFmLxnlbQytqNkW64F60t1icF3jR2RHnJUw?key=tOpRLWBNQc5MC-6EZzpns8xM)
Finally, the tab "**Cohort Zygosity**", on the variant table, reports exclusively the names of the samples carrying the variant, also color-coded in red or green font to inform about the sample status and their respective type of zygosity. Note that this tab appears in all multi-sample analyses, even those with fewer than 10 samples.
[](https://lh7-rt.googleusercontent.com/docsz/AD_4nXfy7w7zELX4CJt0ijRCwbIyKzNpcufHHKY9YdFE5lpbP8fLOpDbEnAXbX3773Wr2x0CyPMknNx_RZY_zBlOV0BUCyG0PNrsezb8nuZ-lfORWjCBQJzYHq9_bRN8loXci6etrezBgwmJbPym1l9jDRY?key=tOpRLWBNQc5MC-6EZzpns8xM)
- [Registration & Billing](https://docs.varsome.com/en/registration-billing?hsLang=en#main-content)
- [User account management](https://docs.varsome.com/en/registration-billing?hsLang=en#user-account-management)
- [Storage management](https://docs.varsome.com/en/registration-billing?hsLang=en#storage-management)
- [Pricing and Billing](https://docs.varsome.com/en/registration-billing?hsLang=en#pricing-and-billing)
- [VarSome Clinical Tokens](https://docs.varsome.com/en/registration-billing?hsLang=en#varsome-clinical-tokens)
- [Management of Samples and Analyses](https://docs.varsome.com/en/management-of-samples-and-analyses?hsLang=en#main-content)
- [Uploading files](https://docs.varsome.com/en/management-of-samples-and-analyses?hsLang=en#uploading-files)
- [Managing Samples](https://docs.varsome.com/en/management-of-samples-and-analyses?hsLang=en#managing-samples)
- [Managing Workflows](https://docs.varsome.com/en/management-of-samples-and-analyses?hsLang=en#managing-workflows)
- [Launching analyses](https://docs.varsome.com/en/management-of-samples-and-analyses?hsLang=en#launching-analyses)
- [Analysis of the results](https://docs.varsome.com/en/analysis-of-the-results?hsLang=en#main-content)
- [Analyses](https://docs.varsome.com/en/analysis-of-the-results?hsLang=en#analyses)
- [Results](https://docs.varsome.com/en/analysis-of-the-results?hsLang=en#results)
- [Filters](https://docs.varsome.com/en/analysis-of-the-results?hsLang=en#filters)
- [Reporting](https://docs.varsome.com/en/analysis-of-the-results?hsLang=en#reporting)
- [Quality Control](https://docs.varsome.com/en/analysis-of-the-results?hsLang=en#quality-control)
- [Legal & compliance](https://docs.varsome.com/en/legal-compliance?hsLang=en)
- [FAQ & Troubleshooting](https://docs.varsome.com/en/faq-troubleshooting?hsLang=en#main-content)
- [Troubleshooting](https://docs.varsome.com/en/faq-troubleshooting?hsLang=en#troubleshooting)
- [General](https://docs.varsome.com/en/faq-troubleshooting?hsLang=en#general)
- [Filters](https://docs.varsome.com/en/faq-troubleshooting?hsLang=en#filters)
- [User Interface](https://docs.varsome.com/en/faq-troubleshooting?hsLang=en#user-interface)
- [Pipelines](https://docs.varsome.com/en/faq-troubleshooting?hsLang=en#pipelines)
- [Features](https://docs.varsome.com/en/faq-troubleshooting?hsLang=en#features)
- [Scientific articles](https://docs.varsome.com/en/scientific-articles?hsLang=en)
- [VarSome API](https://docs.varsome.com/en/varsome-api?hsLang=en)
[](https://varsome.com)
**Resources**
[Query Examples](https://varsome.com/about/resources/examples/)
[Germline Classification](https://varsome.com/about/resources/germline-implementation/)
[Somatic Classification](https://varsome.com/about/resources/somatic-implementation/)
[White Papers & Other Resources](https://varsome.com/library/)
[Cite VarSome](https://varsome.com/about/general/varsome-citations/)
[System Status](https://status.saphetor.com/)
[Help Center](https://docs.varsome.com/en?hsLang=en)
**Legal**
[Terms of Use](https://varsome.com/information/legal/terms/)
[Privacy Policy](https://varsome.com/information/legal/privacy/)
[Information Security](https://varsome.com/information/legal/information-security/)
Copyright © 2025, Saphetor SA