Algorithmic filters

Algorithmic filters are very powerful filters allowing you to perform more complex variant filtering. These filters can be fully customized by our experts according to specific needs of your workflow. Use cases for Algorithmic filters are almost infinite; below you may find some common examples:

  • Recessive candidates
  • ACMG Actionable Gene
  • Carrier risk for couples
  • Compound Heterozygous + homozygous
  • Compound Heterozygous Candidates
  • Compound Heterozygous Segregating Variants
  • De novo (noSupportingReads)
  • De novo (NP+Fisher+MinCov)
  • De novo (strict)
  • De novo candidates (naive)
  • Segregating Variants (dominant)
  • Segregating Variants (recessive)
  • Variants common to all affected samples

You can access Algorithmic filters under Launch analysis > Algorithmic filter analysis:


Once on the page with the list of all Algorithmic filters, you can always click on the blue circle to learn about details of each Algorithmic filter:

Details of Algorithmic filter

In other words, Algorithmic filters create a snapshot of the parent analysis, with a filtered subset of variants, according to each Algorithmic filter. Later on, you lay over Dynamic filters to fine-tune the list of your variants.

You can also find demonstrated examples of how to apply them in your analyses.